The objectives of KinaseDetect are to provide pharmaceutical and other drug developing companies, as well as public research institutions with protein kinases and proteins for exploring signal transduction pathways involved in various diseases, e.g. cancer, neurodegenerative disorders etc.
Also KinaseDetect provide pharmaceutical companies with protein kinase activity data by testing selected potential drug candidates (protein kinase antagonists) after high throughput screening .
Objectives and Services:
Protein Kinases and Proteins:
KinaseDetect supplies a variety of protein kinases and related proteins.
These proteins are crucial for studying signal transduction pathways, which are involved in the regulation of cellular processes.
Research in these pathways can lead to a better understanding of diseases like cancer and neurodegenerative disorders.
Protein Kinase Activity Data:
The company tests potential drug candidates, specifically protein kinase antagonists, to determine their activity.
This testing occurs after a high throughput screening process, which helps identify promising compounds.
The activity data provided by KinaseDetect assists pharmaceutical companies in selecting and developing effective drugs.
Importance in Drug Development:
Cancer Research: Protein kinases play a critical role in the regulation of cell growth and division. Abnormal kinase activity is often linked to cancer. By studying these kinases, researchers can identify targets for cancer therapies.
Neurodegenerative Disorders: Kinases are also involved in signaling pathways within the nervous system. Understanding these pathways can lead to the development of treatments for diseases like Alzheimer's and Parkinson's.
High Throughput Screening (HTS):
HTS Process: This is a method used to quickly conduct millions of chemical, genetic, or pharmacological tests. Through HTS, researchers can identify active compounds, antibodies, or genes that modulate a particular biomolecular pathway.
Role of KinaseDetect: After the initial screening, KinaseDetect further tests selected compounds to provide detailed activity data, ensuring that the most promising candidates are prioritized for development.
Impact:
By providing these specialized tools and data, KinaseDetect accelerates the drug discovery process.
Their work helps in the early identification of potential drug candidates, reducing the time and cost associated with bringing new therapies to market.
Collaboration with both pharmaceutical companies and public research institutions ensures a wide application of their services, fostering innovation and advancements in medical research.
